Brand: Desyrel Dividose

Drug Type: SSRI/ Antagonist, Antidepressants

Form: Tablet

Age limit: 18 years and above

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Desyrel 50 mg Tablet Trazodone is an SSRI antidepressant or selective serotonin reuptake inhibitor. It increases the brains production of serotonin, which aids with mood regulation.

Some people who take trazodone will notice a change in mood within one to four weeks, but it may take a few months to see all of its benefits. Before your mood improves due to the intake of trazodone, side effects are possible.

Children below the age of 18 should refrain from this medication. 


Administer Desyrel 50 mg Tablet by mouth once daily before bed. It is recommended for use after a light snack or proper meal. The extended-release tablet is taken without a meal. 

The dosing instructions and the intake instructions are explained to the patient. It is in addition to the side effects of the drug.  One should take this medication until the doctor sees fit. The doctor is in charge of the prescription. 


The side effects of taking Desyrel 50 mg Tablet appear differently in different people. A higher dose of the medication could result in adverse side effects- the effects mentioned below. 

  • Blurred vision
  • Stuffy nose
  • Headache
  • Muscle pain
  • Dizziness
  • Changes in weight
  • Dry mouth

The physician knows how to manage the side effects. If the medicine is not taken duly, then more side effects occur. 

Rare side effects may occur in some patients. It is tough to judge the side effects that may arise. 


The dosage depends on severity and patients response. 

It is advised to start with 150 mg daily, divided into two dosages. Beginning with a modest dose, the dosage should be increased gradually while taking note of the clinical response and any signs of intolerance. Drowsiness may call for the administration of majority of the daily dose at bedtime or a dosage reduction.

The dose may be raised by 50 mg daily every three to four days three to four days, the dose may be raised by 50 mg daily. For outpatients, the daily dose cap is typically 400 mg divided into two doses. Inpatients (i.e., those with who are inpatients (i.e., those who have more severe depression) may get up to but not more than 600 mg daily divided doses.

Depending on the therapeutic response, the dosage may be decreased gradually once a satisfactory answer has been established.


  1. The doctor is aware of all the patients medical problems like kidney and liver problems.
  2. Adverse side effects of combining Desyrel 50 mg Tablet with other medicines exist. Book an appointment with the doctor if these side effects occur.
  3. It is essential to be aware that trazodone may cause angle-closure glaucoma (a condition where the fluid is suddenly blocked and unable to flow out of the eye causing a severe increase in eye pressure). Ask your doctor if you should get your eyes checked before beginning this medicine. Call your doctor or get emergency medical attention imediately if you are experiencing nausea, eye pain, changes in your vision, such as seeing colored rings around lights, or swelling or redness in or around your eyes.
  4. You should be aware that trazodone may result in lightheadedness, fainting, and dizziness if you stand up suddenly from a laying posture. It is best to get out of bed gradually, resting the feet on the floor for a few minutes before standing up. 
  5. Inform your physician if you have ever experienced long QT syndrome (a rare heart condition that can result in irregular heartbeat, fainting, or sudden death). The same holds true if you have ever had a heart attack, or low sodium levels in your blood. You should also mention any history of heart disease in your family.   

The doctor is the authority on what to avoid when taking this medication. Some precautions heeded are for a better outcome.


Desyrel 50 mg Tablet interacts with other medicines and can reduce the effectiveness of the medication taken. The doctor informs the patient about the drugs that should not be mixed. The other drugs it interacts with stated below:

  • Phenytoin
  • Antidepressants
  • Warfarin
  • St John’s Wort
  • Sumatriptan
  • Tramadol 
  • Maxalt
  • Treximet
  • Jantoven

Being mindful of the drugs and their uses is essential. Mania, Hypotension, and Seizures interact with this drug. 


Active Ingredients Inactive Ingredients
Trazodone Hydrochloride  Polysorbate 80
Anhydrous lactose
Polyethylene glycol
No. of Pills

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