Brand: Mestinon

Drug type: Acetylcholinesterase inhibitor

Form: tablets

Age limit: 18 years above.

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Mestinon tablet is a prescription drug recommended to treat myasthenia gravis. Myasthenia gravis is a skeletal muscle disease where skeletal muscle gets weaker and worsens as time passes. Pyridostigmine is an active ingredient that improves muscle strength by preventing the breakdown of a natural body substance which is Acetylcholine. Acetylcholine maintains muscle function.


Mestinon tablet by mouth with or without food, but it’s better to take it with food. Take a full glass of water with each dose of the medicine to avoid stomach irritation. Do not cut, bite or triturate the tablet and swallow it thoroughly. Read the information mentioned; on the user leaflet and follow the doctor’s instructions.


Everyone may experience different side effects depending upon dose concentration and frequency. Here are a few common side effects:

  • Upset stomach
  • Nausea
  • Heartburn
  • Dizziness
  • Drowsiness
  • Diarrhea
  • headache

Tell your doctor if you are allergic to any ingredient present in the medicine. It may cause severe side effects.

Here are a few severe side effects:

  • Slur speech
  • Sore throat
  • Dark color urine
  • Blur vision
  • Weight gain (rare)
  • Liver diseases( rare)
  • Trouble in breathing


The dose of Mestinon (pyridostigmine) tablets not only depends on the age but also depends on treatment response as it is a prescription drug. Usually, the dose is prescribed to take 2 times a day, which means 6 hours gap in each dose, or it can be less depending on the disease condition. Do not take an overdose for quick betterment. Otherwise, it may give severe side effects.


Keep at room temperature.

Keep away from sunlight.

Keep away from children.


Avoid Mestinon (pyridostigmine) tablets if you are taking any blood disorder treatment.

Patients with kidney/liver/lung disease or mental disorders like depression and rapid mood swings should tell their doctor about it as more doses of this medicine may cause kidney failure or worsen.

Someone with blood pressure problems or breathing issues should take the doctor’s advice for this medication as it causes an increase in blood pressure which gives undesirable side effects.

Pregnant women and breastfeeding mothers should avoid this medicine because it passes through breast milk and affects the baby’s growth.


This medicine may interact with the following diseases:

  • Bradycardia
  • Bronchospasm
  • Coronary artery disease
  • Parkinsonism
  • Hyperthyroidism
  • PUD


Pyridostigmine bromide Colloidal hydrated silica, maize starch, lactose monohydrate, talc and magnesium stearate.


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