Rx (Prescription medicine)

Brand: Benemid

Drug type: Uricosurics

Form: Tablet

Age limit: 10 years above

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Probenecid 500mg tablet is used for treating gout and gouty arthritis. This medicine will not help with a sudden attack of gout. The active ingredient Probenecid lowers the uric acid concentration in the body by helping the kidney get rid of uric acid. High levels of uric acid form crystals in the joints and cause gout. Lowering uric acid is also better for the kidney.


Administer Benemid 500mg tablets by mouth with food or as instructed by the doctor. Usually, it is recommended twice daily. Take a full glass of water with each dose of the medicine to avoid stomach irritation. Do not cut, bite or triturate the tablet and swallow it thoroughly. Read the information mentioned; on the user leaflet and follow the doctor’s instructions.


Everyone may experience different side effects depending upon dose concentration and frequency. Here are a few common side effects:

  • Upset stomach
  • Nausea
  • Heartburn
  • Dizziness
  • Drowsiness
  • Diarrhea
  • headache

Tell your doctor if you are allergic to any ingredient present in the medicine. It may cause severe side effects.

Here are a few severe side effects:

  • Lower back pain
  • Painful urination
  • Swelling on legs
  • Sore throat
  • Skin rash


The dose of Probenecid 500mg tablets not only depends on the age but also depends on treatment response as it is a prescription drug. Usually, the dose is prescribed to take when there is extreme pain, then it is 2 times a day, or it can be less depending on the disease condition. Do not take an overdose for quick betterment. Otherwise, it may give severe side effects.


Keep at room temperature.

Keep away from sunlight.

Keep away from children.


Do not take Probenecid 500mg tablets if you are suffering from anaemia.

Patients with kidney/liver/lung disease or mental disorders like depression and rapid mood swings should tell their doctor about it as more doses of this medicine may cause kidney failure or worsen.

Someone with blood pressure problems or breathing issues should take the doctor’s advice for this medication as it causes an increase in blood pressure which gives undesirable side effects.

Pregnant women and breastfeeding mothers should avoid this medicine because it passes through breast milk and affects the baby’s growth.


Benecid 500mg tablet may interact with following drugs:

  • Barcitinib
  • Dyphylline
  • Ketorolac
  • Methotrexate
  • Pyrazinamide
  • Salicylates
  • Zidovudine


Active ingredient – Probenecid 500mg 

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