Sotalol Hydrochloride 160 mg Tablets efficiently treats atrial fibrillation and other heart conditions like arrhythmias. It is strictly a prescription drug and is not available over the counter. It reduces heart rate and causes ‘heart block’. It is available in an oral solution form for people who cannot swallow pills. The dosage instructions for adults and children are specified by the doctor.
WAY OF ADMINISTRATION:
Administer Sotalol Hydrochloride 160 mg Tablets by mouth twice or thrice daily. The doctor examines the situation of the patient and decides the dosage schedule for a stipulated time.
To reach a steady state and enable QT interval monitoring, the oral dosage of sotalol should be progressively increased, with 2-3 days separating each increment. The majority of individuals benefit from a daily dose of 160 to 320 mg given twice at intervals of about 12 hours.
SIDE EFFECTS:
The side effects of taking Sotalol Hydrochloride 160 mg Tablets manifest differently in different people. A higher dose of the medication could result in severe side effects. Some effects are mentioned below.
- Headache
- Fever
- Hypotension
- Dyspnoea
- Tiredness
- Diarrhea
- Chest aches
A visit to the physician is a must if the side effects persist. The doctor is trained to deal with and manage the side effects. Unwanted side effects also occur if the medicine is not taken properly. Side effects and dosage are directly proportional.
The rare side effects may occur in some patients. It is good to focus on immunity and find effective ways to build it up. The side effects may not be so severe for patients in this case.
DOSAGE:
To achieve steady-state plasma concentrations and enable monitoring of QT intervals, the dosage of sotalol hydrochloride tablets, and USP should be adjusted gradually, allowing three days between dosing increments. Gradual dose adjustments will aid in avoiding the use of doses more than are required to control the arrhythmia.
80 mg twice daily is the suggested starting dose. After a suitable review, this dosage may be increased to 240 or 320 mg daily (120 to 160 mg twice daily). Majority of individuals respond therapeutically to a daily dose of 160 to 320 mg administered in two or three separate doses.
480 to 640 mg/day may be necessary for some individuals with life-threatening refractory ventricular arrhythmias. These dosages should only be recommended when the potential benefit justifies the greater risk of side effects, particularly proarrhythmia.
Dosing on a schedule other than a BID regimen is typically not essential due to sotalol prolonged terminal elimination half-life.
WARNINGS/PRECAUTIONS:
- One should not take Sotalol Hydrochloride 160 mg Tablets in the event of asthma, long QT syndrome, and sick sinus syndrome.
- You should spend at least three days at a facility that can offer continuous heart monitoring and kidney function tests before starting or restarting this drug. It will lessen the possibility of experiencing cardiac rhythm issues.
- Sudden discontinuation of this medicine may result in worsening chest pain, issues with heart rhythm, or possibly a heart attack. When discontinuing this medication, one needs close monitoring. Your dosage is decreased gradually. A different beta-blocker may be prescribed, particularly if you have coronary artery disease.
- Avoid alcoholic beverages while using this medication. Sotalol and alcohol can increase your drowsiness and vertigo. Additionally, it may cause abnormally low blood pressure.
- In general, you should not take sotalol or other beta-blockers if one has non-allergic tightness of your airways like chronic bronchitis or emphysema. If you must take this medication, ask your doctor to recommend the lowest dose that will still be effective.
INTERACTIONS:
Sotalol Hydrochloride 160 mg Tablets interact with other medicines and can reduce the effectiveness of the medication taken. The other drugs it interacts with stated below:
- Pimozide
- Clarithromycin
- Tylenol
- Quinidine
- Pradaxa
- Coumadin
- Xarelto
- Xanax
The disease interactions of this medication are also present. PVD, Glaucoma, Hemodialysis, and Bradyarrhythmia interact with this tablet.
INGREDIENTS:
| Active Ingredient | Inactive Ingredients |
| Sotalol Hydrochloride | Pregelatinized starch |
| Lactose monohydrate | |
| Stearic acid | |
| Microcrystalline cellulose |
